North East and North Cumbria
ICS Formulary
 
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4 Central nervous system
04-07-01 Compound analgesic preparations

While Co-codamol 8/500 is commonly used, no advantages over paracetamol have been substantiated. The low dose of codeine may be enough to cause opioid side-effects (in particular, constipation) and can complicate the treatment of overdose, yet may not provide significant additional relief of pain. Use is therefore discouraged.