North East and North Cumbria
ICS Formulary
 
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4 Central nervous system
04-10-03 Opioid dependence

Buprenorphine 400 microgram, 2mg, and 4mg sublingual tablets
Formulary

  • Only approved for use in accordance with NICE guidance. 

  • In the treatment of substance misuse the 400microgram strength should be prescribed as Subutex® to avoid a product licensed for pain relief being supplied

Controlled Drug  Red View adult BNF  View SPC online  View childrens BNF
Buprenorphine and Naloxone Suboxone®
Formulary

Controlled Drug  Red View adult BNF  View SPC online  View childrens BNF
Lofexidine BritLofex®
Formulary
  • Green plus South Tyneside and Sunderland only 

Red View adult BNF  View SPC online  View childrens BNF
Methadone
Formulary
  • Methadone 5mg in 5ml oral solution and 5mg in 5ml sugar free solution are both approved for the management of opioid dependence in line with NICE.
  • Red CD&TV and ST&S

Controlled Drug  Green plus View adult BNF  View SPC online  View childrens BNF
Naltrexone 50 mg tablets Nalorex®
Formulary
  • Approved for the management of opioid dependence in detoxified formerly opioid-dependent people in line with NICE.
  • Also approved NoTGhdNC for use in reducing agitation and/ or selfinjurious behaviour in patients with learning disabilities or autism (unlicensedunlicensed indication). Treatment must be initiated by an appropriate hospital specialist.
Link  NICE TA115: Drug misuse - naltrexone

Red View adult BNF  View SPC online  View childrens BNF