North East and North Cumbria
ICS Formulary
 
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5 Infections
05-02-01 Triazole antifungals

Fluconazole Oral Preparations
Formulary
  • Capsules: 50mg, 150mg, 200mg
  • Oral solution: 50mg/5ml, 200mg/5ml 

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Itraconazole Oral Preparations
Formulary
  • 100mg capsules 
  • 50mg in 5ml oral solution 

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Fluconazole Infusion
Formulary
  • IV infusion: 50mg/25ml, 200mg/100ml

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Isavuconazole Cresemba®
Formulary
  • Approved for use in line with licensed indications and specifically in solid organ transplant and bone marrow transplant recipients.

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Itraconazole Infusion
Formulary
  • 250mg in 25ml injection for IV infusion 

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Posaconazole  Noxafil®
Formulary
  • Approved for the prevention of invasive fungal infection in immunocompromised patients in whom there is a specific risk of aspergillus infection or where fluconazole and itraconazole are not tolerated or are unlikely to be sufficiently effective (largely for secondary prevention).
  • Approved for patients with invasive fungal infections that are not responding to other treatments or where they are not tolerated (largely in place of liposomal amphotericin/ voriconazole).

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Voriconazole
Formulary
Link  MHRA Safety Alert (May 2014): Voriconazole: reminder of liver toxicity, phototoxicity and squamous cell carcinoma

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