North East and North Cumbria
ICS Formulary
 
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7 Obstetrics, Gynaecology, and urinary-tract disorders
07-04-05 Drugs for erectile dysfunction

Sildenafil
First Choice
  • Approved for the treatment of erectile dysfunction
  • Also approved for specialist use in treating:
    • Pulmonary hypertension (see section 2.5.1a) Red Traffic Light
    • Secondary Raynaud’s disease. Green plus
Link  MHRA Drug Safety Update (Nov 2018): Sildenafil (Revatio and Viagra): reports of persistent pulmonary hypertension of the newborn (PPHN) following in-utero exposure in a clinical trial on intrauterine growth restriction

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Tadalafil
Second Choice
  • 10mg and 20mg tablets
    • Approved for the treatment of erectile dysfunction
    • Also approved for specialist use in treating secondary Raynaud's disease. Red Traffic Light
  • 5mg tablets (once daily) 
    • Approved for the treatment of erectile dysfunction (in accordance with SLS criteria)
Link  NTAG: Daily vs on-demand phosphodiesterase-5 (PDE-5) inhibitors for the management of erectile dysfunction following treatment for prostate cancer

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Vardenafil
Formulary
  • 5mg, 10mg and 20mg tablets

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Alprostadil Vitaros® & Muse®
Formulary
  • Vitaros® 3mg/g cream
  • Muse® 500microgram, and 1mg.

Treatment with alprostadil cream (Vitaros®) is NOT approved for use in County Durham and Tees Valley


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Aviptadil 25microgram/phentolamine 2mg solution for injection Invicorp®
Formulary
  • 25microgram/phentolamine 2mg solution for injection. 
  • Approved as first choice intracavernosal injection option.

 

 


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Alprostadil Caverject® & Viridal Duo®
Formulary
  • Approved as the second choice intracavernosal injection option.
  • Caverject® 10 & 20 microgram injections (Caverject® dual chamber injections are easier to use and less expensive than the vials).
  • Viridal Duo® 10, 20 and 40 microg starter pack and dual chamber injection (approved for use whilst supply issues surrounding Caverject® are ongoing).

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